Alcohol-related conditions result in a significant economic burden due to the loss of productivity as well as the cost of treatment of alcohol-related disorders and injuries. Globally in 2016, there were 99.2 million disability-adjusted life-years (DALYs), and 4.2% of all DALYs were attributable to alcohol use. On the other hand, the harmful use of alcohol is a leading public health concern worldwide that results in millions of deaths consequent to non-communicable diseases and injuries. Conclusions: While using the DSM-5 criteria would result in a lower prevalence of AUD in Singapore, it remains a highly comorbid condition associated with a poor health-related quality of life that is largely untreated, which makes it a significant public health concern.Īlcohol use has become embedded in social practices globally, with moderate use shown to enhance positive affect and bonding. Both DSM-IV and DSM-5 AUD were associated with significant comorbidities in terms of other mental disorders however, those diagnosed with lifetime GAD had significantly higher odds of having DSM-5 AUD (AOR, 5 95% CI 1.9–13.2) but not DSM-IV AUD. However, those who were economically inactive (versus employed) (AOR, 0.4 95% CI 0.2–0.9) and had a higher monthly household income (SGD 4000–5999 versus below SGD 2000) had lower odds of DSM-IV AUD (AOR, 0.4 95% CI 0.2–0.7), but this was not observed among those with DSM-5 AUD. Younger age, male gender, and lower education were associated with higher odds of both DSM-IV and DSM-5 AUD. Results: The lifetime prevalence of DSM-IV AUD was 4.6% (0.5% for dependence and 4.1% for abuse) in the adult population, while the lifetime prevalence of DSM-5 AUD was 2.2%. Associations between DSM-IV/DSM-5 AUD, chronic conditions, and the HRQOL summary scores were examined using logistic and linear regression after controlling for significant sociodemographic factors. Sociodemographic correlates of lifetime DSM-IV/DSM-5 AUD were examined using multiple logistic regression analysis. Lifetime DSM-IV AUD diagnoses were compared with DSM-5 AUD diagnoses generated by modifying the criteria and the addition of the craving criterion. Methods: Respondents were assessed for lifetime mental disorders using the Composite International Diagnostic Interview (CIDI) administered through face-to-face interviews. The current study aimed to evaluate the consequences of the modification of the diagnostic criteria from DSM-IV to DSM-5 AUD using lifetime diagnosis in Singapore’s multi-ethnic population using data from a nationwide epidemiological study. Following this shift in diagnostic criteria, a difference in the prevalence of AUD was expected. Introduction: The Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) criteria for alcohol use disorders (AUD) was a significant shift from the historical DSM-IV Text Revised version.
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